CHANGES IN BLOOD PARAMETERS IN BREEDER TOMS FOLLOWING SUBCUTANEOUS INJECTION WITH CADMIUM

Abstract

Alterations in blood biochemical values of Yearling breeder toms following parenteral administration of cadmium (Cd) were well evaluated. Each treated member of a pair of (total 24 pairs) 0f toms received a single dose of 4.5mg of Cd per kg. body weight (0.04-mole). The birds were sacrificed at 0,6,24 and 192 hours : post-treatment. Highly significant (P<0.0001).increase in serum Cd concentration was observed in the Cd-injected toms, Reduction in the blood have been used to produce useful serum Cd (P<0.05) at the successive post-necropsy periods indicated systematic clearance of the metal from the fluid. Nearly 50 percent eliminated by 24 h post-treatment. Serum changes glutamic pyruvic transaminase (SGPT) was due to the similarly increased (P<0.05) in the Cd-treated birds and was presumed to have originated mainly from damaged skeletal muscle tissues. The cadmium treatment did not affect (P>0.05) serum testosterone level, total protein, total haemoglobin, lactate dehydrogenase, packed cell volume or serum glutamic oxaloacetic transaminase. It was concluded from these observations that the Cd treatment did not seem to have interfered seriously with renal or hepatic functions, iron, copper and zinc metabolism or caused significant damage to myocardial issue.