THE STABILITY OF WET T1 CONTAGIOUS BOVINE PLEUROPNEUMONIA VACCINE

Abstract

THE stability of wet T₁ contagious bovine plenropneumonia (CBPP) Vaccine stored at 4^°C was studied. Two large batches of the vaccines were stored at 4°C for up to 5 months. From the third month of storage, the vaccines were used to vac­cinate CBPP-free animals. The immune levels of the animals were monitored by complement fixation test (CET) and challenge trial. The results indicated that all the vaccinated animals produced reasonable an­tibody titres even after 5 months storage. Also, all the animals vaccinated with vaccines stored between 3 to 5 months resisted infection by contact while ail the incubated and control animals came down with the disease. The results indicated that the vaccine could actually be stored for up to 5 months at 4°C before use.