IN SILICO ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISM (SNPs) IN RABBIT GROWTH HORMONE

Authors

  • S. I. Musa Faculty of Agriculture, Nasarawa State, University, Shabu-Lafia Campus

DOI:

https://doi.org/10.51791/njap.vi.4081

Keywords:

Growth hormone, Rabbit, Polymorphism, Prediction, In silico

Abstract

The main objectives of this research were to evaluate the molecular structure and predict the effect of single nucleotide polymorphism in rabbit growth hormone. Analysis using protparam server indicated molecular weight of 24433.06, estimated half life of 30 hours, instability index of 36.04 and aliphatic index of 86.39. Secondary structure prediction showed 30% disordered , 69%alpha helix and 0% beta strand. Analysis of single nucleotide polymorphism indicate that substitution of leucin for valine at position 36 has adverse effect on the fuction of rabbit growth hormone. It can be concluded that single nucleotide polymorphism can be used as genetic markers for selection in rabbit breeding.

Author Biography

S. I. Musa, Faculty of Agriculture, Nasarawa State, University, Shabu-Lafia Campus

Department of Animal Science

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Published

2024-07-08

How to Cite

Musa, S. I. (2024). IN SILICO ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISM (SNPs) IN RABBIT GROWTH HORMONE. Nigerian Journal of Animal Production, 14–17. https://doi.org/10.51791/njap.vi.4081

Issue

2022: NSAP 2022 Proceedings

Section

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