Antibacterial Activity of Ethanolic Extract of Pleurotus ostreatus on Selected Pathogenic Organisms

Abstract

The antibacterial activity of an ethanolic extract of Pleurotus ostreatus in four various concentration (25, 50, 75 and 100 ml) was investigated against 3 species of bacteria: one Gram-positive bacteria (Staphylococcus aurues) and two Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) using the minimum inhibitory concentration. Data obtained on minimum inhibition concentration were arranged in one way analysis of variance. The result showed that 100 ml of Pleurotus ostreatus had the highest minimum inhibitory concentration on the bacteria especially on the multi-drug resistant bacteria Pseudomonas aeruginosa compared to other concentrations. Pleurotus ostreatus can be used in the treatment of the studied bacterial organisms especially for Gram-negative bacteria of Pseudomonas aeruginosa ATCC®27853which is a multi-drug resistance as a replacement for antibiotics.