An in vivo assessment of the use of Haematopan B12 in the treatment of experimentally induced anaemia in domestic rabbits.

Résumé

A total of 15 domestic rabbits divided into 3 groups of 5 animals per group were used in this study Group A animals (control) were not bled but those in groups B and C were bled to induce anaemia. Group B were left to recover by normal haemopoiesis while those in group C were treated with Hematopan B12*, a commercially prepared haematinic. The post-bleeding treatment haematologic values were obtained at given intervals (7 days) and compared with the pre-bleeding values earlier obtained. The result of this study showed that the group B animals recovered gradually by physiologic haemopoeisis while animals in group C showed accelerated recovery since these animals had a better and faster response in terms of white blood cell (WBC), red blood cell (RBC) count and haemoglobin (Hb) concentration. Thus Haematopan B12 is an effective haematinic.